This poor queen! Locked up for most of her life, diagnosed as “insane” when there was probably nothing wrong with her at all. Her nephew was Charles V, emperor of practically everything in Europe that wasn’t France or England. Her niece was Katherine of Aragon, wife of Henry VIII. Queen Jane, Juana La Loca, Crazy Jane–all those high connections, and no one ever lifted a finger to help her. History can sometimes make for harrowing reading. That’s Original Sin for you.
https://leeduigon.com/2015/09/18/crazy-jane-the-queen-of-spain/